The Benefits of Bio-Synergy® Beta-Performance™ HMB: Backed by Science Since the 1990s
If you’re looking for faster recovery, reduced muscle breakdown, and improved strength gains, you’ve probably heard of HMB (beta-hydroxy beta-methylbutyrate). But did you know that Bio-Synergy® was one of the first brands in the world to research and develop HMB supplements — way back in the 1990s?
In this post, we’ll share:
- What HMB is and how it works
- Highlights from our pioneering 1990s University of London study
- The latest 2022 research in professional athletes
- Why Bio-Synergy® Beta-Performance™ HMB still leads the field today
What is HMB and Why Do Athletes Use It?
HMB is a metabolite of the essential amino acid leucine, known for its role in muscle protein synthesis. Research shows HMB helps:
- Reduce muscle protein breakdown during intense training or calorie restriction
- Support muscle repair by activating mTOR and IGF-1 pathways
- Lower markers of muscle damage like creatine kinase (CK) and lactate dehydrogenase (LDH)
- Improve recovery time and training consistency
Our Groundbreaking 1990s HMB Research
In the late 1990s, Bio-Synergy® worked with the University of London and Royal Free Hospital to study calcium HMB supplementation in resistance-trained athletes.
Study details:
- Participants: 20 experienced male athletes
- Dosages: 1.35g or 2.69g/day of calcium HMB (Bio-Synergy® Beta-Performance™) for 14 days
- Design: Double-blind, placebo-controlled trial
Key findings:
- Significant increases in serum HMB (p=0.009) and urinary HMB (p=0.03) — proving strong bioavailability
- Lower CK levels in higher-dose group — suggesting reduced muscle damage
- No negative changes to blood markers or metabolic health
- Athletes reported faster recovery and reduced soreness
Modern Science Confirms the Benefits
Fast forward to 2022, and a published study on professional football players found that short-term HMB free acid (HMB-FA) supplementation significantly reduced CK and LDH after a simulated match.
Highlights from the 2022 study:
- Reduced muscle injury indices — better recovery potential
- Mechanisms include increased satellite cell activation, muscle hypertrophy, and reduced protein breakdown
- Effective for both trained and untrained individuals, though elite athletes see best results over longer cycles
Why Choose Bio-Synergy® Beta-Performance™ HMB?
Bio-Synergy® has been at the forefront of HMB research and supplementation for over 25 years. Our Beta-Performance™ HMB formula is designed to:
- Protect lean muscle mass during training and calorie deficits
- Enhance strength and power gains alongside resistance training
- Improve training frequency by reducing DOMS
- Support safe, long-term use with no adverse effects on metabolic health
Who Can Benefit from HMB Supplementation?
HMB is ideal for:
- Strength and power athletes
- Footballers, rugby players, and other team-sport athletes
- Endurance athletes during high-intensity phases
- Those recovering from injury or immobilization
- Older adults maintaining muscle mass
The Bio-Synergy® Advantage: Proven Before It Was Popular
When you choose Bio-Synergy® Beta-Performance™ HMB, you’re getting more than just a supplement — you’re getting decades of proven results. We helped introduce HMB to the sports nutrition world, and we’re still leading the way in quality, purity, and scientific backing.
References:
- Hughes S., Sanford E., et al. (1999). Biochemical and haematological effects of β-HMB supplementation. University of London & Royal Free Hospital.
- Rezaeimanesh D., et al. (2022). Response of muscle damage indices to short-term supplementation of HMB-FA in professional soccer players. doi:10.47750/pnr.2022.13.01.013
💪 Ready to recover faster and perform better? Try Bio-Synergy® Beta-Performance™ HMB — the scientifically proven HMB supplement.